Crohns and Inflammatory Bowel Disease (IBD) are conditions that affect the digestive tract from the mouth to the anus. More frequently patients experience symptoms in the small and large intestines that involve ulcerations, fistulas, abdominal pain and cramping.

Although researchers and scientists dont have a conclusive reason for the development of IBD they do have several theories and know some risk factors for Crohns and IBD.

Researchers theorize that potential causes include low stomach acid, autoimmune issues, genetic predisposition or bacterial infections. More recently investigators from Massachusetts General Hospital have identified several genetic variations associated with Crohns disease. This discovery of new genetic risk factors can improve the understanding of the disease and reveal new pathways for treatment. This study takes advantage of new knowledge of genetic variations.

Its estimated that one to two million Americans suffer from IBD. Crohns is considered to be the second most common inflammatory condition only to rheumatoid arthritis.

Inflammatory Bowel disease often runs in families which gave researchers the clue to look at genetic factors. The incidence varies depending upon sex, age and place of residence.

Some researchers believe that risk factors for Crohns and IBD do not include gender while others think there may be a slightly greater risk for women. People of Jewish descent have a slightly higher risk while people of African American descent have a decreased risk.

In general the highest age for risk of Crohns and IBD are between the years of 20 and 30 but it can be diagnosed when you are younger or older. Another peak is between age 50 and 80. Another risk factor for Crohns and IBD is living in the city versus living in the country. Also, Western industrialized nations have a higher incidence then less develop countries indicating the not only does genetics play a role but also environment and diet as well.

Although scientists and doctors have identified certain risk factors for Crohns and IBD the exact causative factor remains elusive. Considering the significantly decreased numbers of people suffering from IBD in non-industrialized nations a closer look at dietary changes and lifestyle changes may help to not only decrease the risk factors for developing these conditions but also to improve the ability of the body to go into remission where the person doesnt experience the symptoms and the colon and small intestines arent subject to as much damage.